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Biosketch:
Dr Ruan Yijun is currently the Senior Group Leader and Associate Director of Genomics Technology at the Genome Institute of Singapore. His primary interest is to elucidate the structures and dynamics of all functional DNA elements in complex genomes through transcriptome characterizations and genome interrogation. To facilitate such understanding, Dr Ruan's lab have developed paired-end-ditag (PET) based high throughput and high precision DNA sequencing and mapping methodologies. These sequencing-based measurements are used to address complex biological questions such as how cancer cells progress and how stem cells maintain their unique properties. Another major interest of Dr Ruan is to discover previously uncharacterized microbial genes and genomes that are relevant to human health. To this end, his lab has established a metagenome analysis capability that includes a filtration system for isolating uncultured microbes, shotgun and PET sequencing of metagenomes to uncover viral and bacterial genome sequences from a variety of environment settings and cavities of the human body. |
