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Biosketch:
Pierre Renault, PhD, is Research Director at the Micalis Institute located in Jouy en Josas (Ile-de-France) in the National Institute for Agronomical Research (INRA). Micalis is composed of 29 teams working in Ecosystem, Food Risk and System Biology applied on Food and Health. In particular, it develops researches on the impact on health of human intestinal microorganisms, which could be collectively named our "second genome", and which genetic variability largely encompasses that of our "first genome".
P. Renault first worked for 2 years to settle a microbiological laboratory in Yemen. Then he performed a PhD on genetics and physiology of food bacteria. From 3 years he redirected its activities on human intestinal microorganisms that intimately interact with human physiology and may protect or favor metabolic disorders in conjunction of changes induced by diet, lifestyle and health.
The BAC team, managed by P. Renault, has a strong background in gene expression and bacterial physiology. It develops metagenomic approaches to establish relationships between components of the human intestinal microbiome and metabolic disorders such as obesity and inflammatory bowel diseases. This includes bioinformatic analysis of data generated by the New Generation Sequencers such as SOLiD and illumina, but also functional approaches on human intestinal microorganisms to pinpoint molecular mechanisms involved in the crosstalk between human and microbiota. These researches may open new ways for personalized medicine. |
