HGM 2011 - Dubai, UAE

Programme

Speakers

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Travel Award

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Martin L. Hibberd

Title: Human - Pathogen interactions and their outcomes, a tale of two or more genomes and their variations

The recent advent of genomic approaches for pathogen sequencing and human association testing is starting to enable a more comprehensive understanding of the role of human immune response in determining infectious disease outcomes, why severe disease is usually rare occurrence. These new approaches are leading to the robust discovery of a number of disease susceptibility genes, the beginnings of an appreciation of their connections and are starting to dissect pathogen-specific human responses.

In particular, the availability of deep sequencing technologies has revolutionized the field of microbial genomics as we are now able to generate genomic assemblies of tens to hundreds of related genomes in a single project. This dense genetic information from multiple microbial strains is enabling novel insights into their population structures and their evolution, ranging from the delineation of disease outcomes, to transmission patterns. In Singapore, we have teamed up with the Ministries of Health, Environment and Defense; together with local hospitals, to apply this knowledge to infectious disease outbreaks, resulting in unique understandings of human interactions.

Sheikh Hamdan Bin Rashid Al Maktoum
Award for Medical Science

Human Genome Organisation

Centre for Arab Genomic Studies